Minocycline in Major Depressive Disorder: And overview with considerations on treatment-resistance and comparisons with other psychiatric disorders
نویسندگان
چکیده
Evidence on the link between immune system and Major Depressive Disorder (MDD) has led to explore antidepressant properties of anti-inflammatory drugs. Among these, minocycline been identified as a potential novel treatment for MDD, in particular treatment-resistant depression. The aim current paper is review pre-clinical clinical evidence efficacy minocycline. includes considerations role both peripheral central inflammation response comparisons across different psychiatric disorders (i.e., unipolar depression, bipolar schizophrenia).
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ژورنال
عنوان ژورنال: Brain, Behavior, & Immunity - Health
سال: 2021
ISSN: ['2666-3546']
DOI: https://doi.org/10.1016/j.bbih.2021.100335